Delete spector pro1/31/2024 ![]() Performance mode made less of a difference in this benchmark. Its scores across the various PCMark 10 categories, including Essentials, Productivity, and Content Creation, were in line with this result. Mark Coppock/Digital Trendsįinally, in PCMark 10 Complete, the Spectre x360 16 came in at third-slowest. It beat its predecessor but was considerably slower than the rest of the group at 378 (416 in Performance mode). I also ran the Pugetbench benchmark that operates within a live version of Adobe Premiere Pro, and the Spectre x360 16 was once again underwhelming. The Spectre x360 16 did a little better in Cinebench R23, beating out the Spectre x360 15, but falling way behind laptops equipped with 45-watt CPUs.Īgain, Performance mode gave a stronger showing at 6,328 in multi-core mode. ![]() Performance mode produced a stronger 177 seconds, still the second-slowest showing. In our Handbrake test that encodes a 420MB video as H.265, the Spectre x360 16 was well behind the rest of the group, including the Spectre x360 15. Its performance is sure to be further eclipsed once Intel’s 12th-gen CPUs start rolling out. Performance mode does make a difference, bumping the Geekbench score to a slightly more competitive 5,278 in multi-core mode. I ran all the benchmarks in both Balanced and Performance modes and recorded the Balanced results here. I’ll note here that HP has its Command Center utility that can switch performance between the automated Smart Sense, which I didn’t use, and Balanced, Performance, and Cool modes. In Geekbench 5, the Spectre x360 16 was the slowest in our comparison group, at least in multi-core mode, even falling behind the LG Gram 16 with its Core i7-1165G7. Indeed, it didn’t always keep up with the Spectre x360 15 that utilized a 1oth-gen Core i7-10750H and an Nvidia GeForce 1650 Ti. Overall, the Spectre x360 16 is underpowered compared to some other laptops in the same 15- and 16-inch class. There’s also an Nvidia GeForce RTX 3050 on hand, an entry-level GPU, and you can save several hundred dollars by opting for integrated Iris Xe graphics. That CPU sits in-between Intel’s 11th-gen U-series and 45-watt H-series processors. The Spectre x360 16 missed out on an Intel 12th-gen upgrade by several months, and instead relies on a 35-watt, four-core/eight-thread Core i7-11390H. Wireless connectivity is fully up to speed at Wi-Fi 6E and Bluetooth 5.2. Power is provided by a proprietary 130-watt charger connection, leaving both USB ports for connecting peripherals. The company’s in-bag detection is now in its second generation as well, promising to avoid the laptop waking up and overheating in a backpackĬonnectivity is decent, with two USB-C with Thunderbolt 4 ports (one of which is conveniently located in the notch at the rear of the chassis), a full-size HDMI 2.0b port, a USB-A 3.2 Gen 2 port, a microSD card reader, and a 3.5mm audio jack (located in the other notch). HP implemented the second generation of its thermal management with the Spectre x360 16, naming it Intelligent Smart Sense 2.0, and it’s intended to improve performance by automatically optimizing performance versus fan noise and chassis heat. It’s equal to the best laptops on the market, such as Dell’s XPS 15, and it maintains the Spectre line’s high standards. Thanks to the use of CNC-machined aluminum, it’s solid as a rock, with no bending or flexing anywhere in the lid, keyboard deck, or chassis. ![]() One thing that hasn’t changed from the previous model is the Spectre x360 16’s build quality. You’ll want to lay the laptop on a solid surface when using it as a tablet with the included active pen. The Spectre x360 16 is manageable in clamshell and media modes, but tent and tablet modes are cumbersome. The MSI Summit E16 Flip, another large convertible 2-in-1, is just 0.67 inches thick and weighs a similar 4.4 pounds. It’s quite a bit deeper than the Spectre x360 15 while being slightly less wide, and it’s 0.78 inches thick compared to 0.79 inches for its predecessor and 4.45 pounds compared to 4.24 pounds. The Spectre x360 16 is a large 2-in-1 thanks to its 16-inch 16:10 display. Thanks to the use of CNC-machined aluminum, it’s solid as a rock.
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Color me crazy coloring book fox1/31/2024 ![]() They are very intelligent and trainable, with loyal, loving personalities. Red Fox Lab Temperamentĭue to their working background, fox red Labs tend to be hard working dogs. ![]() ![]() You may have more luck looking for an American Lab type, from working lines. That doesn’t mean they don’t exist, but for the reasons given above, research your breeder carefully. And if you live in the USA, you may have to do plenty of detective work to find one at all. So if you want a typical English lab with the stocky body and blocky head, you’ll find it more difficult to get an English fox red lab puppy. And because they are often the American Lab type rather than English Lab type, they are often taller and more athletic in appearance than the paler yellow Labs.įox red Labs are mainly the preserve of the working retriever community. It is largely from this pool of working retrievers that we now have the stunning fox red Labrador Retrievers that we see today. Any dog advertised as an English fox red Labrador will probably have a pedigree that is a mix of American and English dogs. Even today you are unlikely to find a Red Labrador with a show background. They have a stronger prey drive, are a little less forward and playful. ![]() American Labs are slimmer built, with less stocky heads and chests. There are two types of Labrador today, the working American Lab and the show bred English Lab. Possibly because a pale yellow dog, being far too easy for wildfowl to spot, is not an ideal hunting companion. Fortunately a pool of dark yellow or fox red Labs remained popular in the working sporting dog community. Especially among the dog showing community. The trend in Labrador coat colors swung to paler and paler colors in the 1970s, and remained that way for decades. Here’s a young red Lab being introduced to the water for the first time. Labradors are some of the world’s most popular hunting companions in addition to their wider roles as service dogs, and most red fox Labs love to explore outdoors and to swim. We’ll also explore the characteristics and care needs of this loyal breed, together with tips for finding a great litter of puppies or adding an older rescue dog to your family. We’ll be sharing our training and exercise tips here to help you get off to a great start with your red fox Labrador puppy. Sometimes known as the ruby Labrador or fox red Lab, these are smart, energetic dogs are best suited to active owners. Breeders are selecting darker red Labrador Retrievers to breed from as they become more popular companions than paler yellow Labs. The red fox Lab, or fox red Lab, is a dark coated variety of the yellow Labrador Retriever. As well as some pale, dilute forms of those colors. Labs come in three colors, yellow, chocolate and black.
Ufo alien invasion script1/31/2024 ![]() James Bond is that you? Aaron Taylor-Johnson appears to be bulking up to become the next 007 spy after entering the race for the role Love Island's Maxwell Samuda speaks out on REAL reason he split from girlfriend Olivia Hawkins just weeks after winter series finished Kevin Costner's estranged wife Christine Baumgartner goes vintage shopping without her wedding ring as she steps out at Loveworn No more meal-time tantrums! Start to ENJOY family dinners again with these delicious 20-minute ideas everyone will love Singer pulls out of King Charles' Coronation concert at last minute due to illness with new star quickly ushered in as replacementĬharlene steals the show! Princess of Monaco is ethereal in a gem-encrusted ensemble as she joins Prince Albert at Buckingham Palace reception Steve Bland's late wife Rachael, the cancer podcaster, just wanted him and their little boy Freddie to be happy - and his story proves new love and life CAN spring from loss One said: 'What about the 10 people getting superpowers? That did not happen.'Īnother wrote: 'What about that big meteor that was supposed to hit the Earth this month?'Ī third noted: 'If it's gonna end soon, then how were you alive in 2671?' This will cause a global black-out and no electricity for six weeks.Īnd in 2027 a worm hole will open up by Mars.īut some viewers are skeptical, saying Eno's previous 'predictions' didn't back up. In 2025, they say the first colonies will arrive on Mars - finding human bones which prove humans first came from the red planet.Īnd in 2026, the largest solar flare in history will hit Earth. The creator has previously made videos about twin planets with Earth, portals opening up to other dimensions, and alien visitors.Īnd they say another global pandemic is on the way - just as the polar icecaps melt away due to global warming.Įno has even offered a year-by-year breakdown of the future. ![]() The account posts more than 397,100 followers, with their videos raking up some 1.6 million likes. In another clip, the 'time-traveler' also predicted that this month would see 'The Lost City of Atlantis' threaten everyone with a 'man made flood, that can cover the entire world'.Įno also alleges that on April 9, a very famous celebrity will reveal that they faked their death, and on June 12 - a earthquake will open a five-mile deep trench which will unveil species previously thought to be extinct. 'I am trying to warn you all of what's to come.' ![]() 'I want you all to know that you are safe,' they reassured. In a previous video, The Distants were branded 'very hostile' and on a mission to take back the planet that's originally theirs.Īpparently, humans became 'more advances than the aliens thought', as Eno claims we will soon be facing them in our firs space battle.Ī 'time-traveler' who warned of an alien abducting 8,000 people on March 23 has now revealed that it has come and gone from Earth. The TikToker explained that they 'own' Earth, and that the Pyramid of Giza is their 'mark of ownership and control'. They also warned that yet another alien species - The Distants - is now on its way to Earth and will arrive sometime next year. 'Such as fighting, and causing the first nuclear winter.' 'Mankind is a threat to itself in many ways,' Eno continued. However, it would seem it's not all good news. ![]() The video went on to claim that the hostages are 'what keep the human species alive, from inside and outside threats'. Stock image usedĪ previous break-down of the abducted suggested it will include around 200 doctors, 1000 farmers, 1000 engineers and mechanics 'and many more'. The captured humans will allegedly protect us from the next alien invasion, which the space-aficionado claims is scheduled for 'mid 2024'. Boycott advance platinum1/31/2024 ![]() The actor mentioned it was a union job, which is a huge factor in determining how much these performers get paid. And I'm a supporting character, I'm not even a main character." the story mode, the arcade mode, and it was a lot of work. It was ‘efforts’, which is getting hit, attacking, and all that. "I had like three sessions, and it was a union game… It was a lot of work. " is slightly more than I got paid for being a supporting character in a fighting game," the actor said. It's worth noting that we spoke to this actor before the Bloomberg report changed the discourse surrounding the Bayonetta situation, when $4,000 was still the primary number being thrown around. We spoke to one voice actor with experience on multiple AAA titles who chose to remain anonymous. What Voice Actors Get Paid, and How Much Work it TakesĪs with any industry, a voice actor's compensation greatly fluctuates depending on the scope of a project and the resources from a studio. So, IGN sought out to learn the following: what is the standard rate for a voice actor, and what is the workload like? IGN spoke to three people in the voice actor industry to find out. Through all of the drama and changes to the story, though, there's still a very real discussion to be had surrounding pay and workload in the voice actor industry. Taylor has since released a new statement, saying she was in fact offered $15,000 for the role. This would have put Taylor's total compensation for Bayonetta 3 at $15,000, much higher than the amount she claimed she was offered. On Tuesday, a report from Bloomberg (and later corroborated by VGC) revealed that Platinum allegedly attempted to hire Taylor for five four-hour sessions at a rate between $3,000 and $4,000 apiece. In the middle of the ensuing social media firestorm, a conversation surrounding voice actor wages in the video game industry started to develop, with some actors sharing their accounts of how much they were paid for taking on certain roles. Wrc 8 cd key1/31/2024 ![]() For example, we will recognize your username and remember how you customized the site during future visits. Functionality cookiesįunctionality cookies let us operate the site in accordance with the choices you make. For example, these cookies let us recognize that you have created an account and have logged into that account. Necessary cookies allow us to offer you the best possible experience when accessing and navigating through our website and using its features. What types of cookies do we use? Necessary cookies It will contain some anonymous information such as a unique identifier, website’s domain name, and some digits and numbers. ![]() Each cookie is unique to your web browser. What are cookies?Ĭookies are simple text files that are stored on your computer or mobile device by a website’s server. By visiting plati.market you agree that plati.market may use cookies to be processed by Google Analytics and Yandex.Metrika. Please read this cookie policy carefully before using plati.market operated by us. With our other products and information about the seller, you can read here
Ps4 remote play 20161/31/2024 ![]() Have you got the Remote Play app set up on your PC or Mac? Let us know in the comments below. 4) Enable Remote Play on your PlayStation 4 by opening Settings > Remote Play Connection Settings and then select the checkbox for Enable Remote. Then alter the settings as required.Īnd that’s all there is to it. Use the DUALSHOCK4 wireless controller on mobile devices with Android 10 or later installed. Use the on-screen controller on your mobile device to control your PS5 or PS4. ![]() To change these on Mac, launch the PS4 Remote Play program, then choose PS4 Remote Play > Preferences> Video Quality for Remote Play from the menu bar. With PS Remote Play, you can: Display the PlayStation5 or PlayStation4 screen on your mobile device. Playing around with these may help you to smooth out any stability issues when using remote play. Here you can change your resolution to either Standard (540p) or Low (360p), as well as the Frame Rate to either a Standard or High option. ![]() To do this, hit the settings option in the bottom left corner of the window before you try and connect to your PS4. You may also want to change the Resolution and Frame Rate settings within the PS4 Remote Play program on your PC. Sony recommends a high-speed connection with upload and download speeds of at least 5 Mbps. If you’re having some sort of technical issue, then it may be down to your internet connection. Hit the register button and you should be all linked up and ready to roll. Simply go into your PS4’s Remote Play Connection Settings, select Add Device and then enter the number displayed on the screen in the empty box on the PS4 Remote Play program on your computer. If, for some reason it hasn’t worked, you can pair your PS4 and computer manually. Connect your computer and PS4 over the same network, and then follow the on-screen instructions. You need to head into ‘Set Features Available in Rest Mode,’ and then select the checkboxes for ‘Stay Connected to the Internet’ and ‘Enable Turning On PS4 from Network’. The final setting we need to make sure is set up right is under the ‘Power Save Settings’. Once this is done, head into the ‘PlayStation Network/ Account Management’ option from the system settings and activate this system as your primary PS4 through the option in this menu. Then select the checkbox for ‘Enable Remote Play’. Head into your system settings and choose the ‘Remote Play Connection Settings’ option. Next, we’ll need to enable Remote Play on your PS4. Open this and it’ll ask you to connect a DualShock 4 controller to your PC or Mac via USB. Run the installation and follow the steps until you find the PS4 Remote Play icon on your desktop. Now that you’ve checked these, go ahead and download the installation tool for Remote Play here.
Gopro quik for mac os1/31/2024 ![]() Either way, you'll get access to updates. You can subscribe to Premiere Rush as a single app, as part of a limited free starter plan, as a bundle with Premiere Pro, or as part of the entire Adobe suite. It's also the best video editing app for professional video editors, because it lets you move content back and forth into Premiere Pro, where you can make more sophisticated edits to it. This cross-platform, video editing app is much easier to use than Adobe's more complex desktop software, such as Premiere Pro, After Effects and Audition. That said, Premiere Rush isn't just for amateurs. That makes it the perfect choice for YouTubers, social media users and anyone wanting to experiment with video editing. ![]() ![]() For example, it automatically converts your videos to the specific aspect ratios and quality levels required by each platform. The focus is on letting you process clips quickly to upload them to social media. You might also want to check out our guides to the best video editing software overall, the best monitor for video editing and the best MacBook for video editing. We'll start with quick links to our top three choices, then continue with detailed pros and cons of all of our picks for the best app for video editing. If you like the sound of that, then also see our guides to best computer for video editing. Some of these apps let you move your clips between mobile devices and computers, too. Most are suitable for both smartphones and tablets (see our guide to best tablets for video editing if you need one of those). In our list you'll find video editing apps for iOS, video editing apps for Android, and apps that can be used on both platforms. Our reviewers have tried out many of the best-known options through hours of editing their own projects, and judged the ease of use, speed, functionality and more to give their honest opinions. We've played with almost every video editing app on this list, so we know they are brilliant for quick tweaks and casual users. Gnuplot fonts1/31/2024 ![]() Will produce an output file that contains valid PostScript, but since it refers to a specialized font, only some printers or viewers will be able to display the specific font that was requested. On the other hand set term postscript eps font "Garamond-Premier-Pro-Italic" Will produce output that is suitable for all printers and viewers. Thus set term postscript eps font "Times-Roman,12" Gnuplot does not know or care about this the output *.ps or *.eps files that it creates will simply refer to whatever font names you request. It is likely that many additional fonts are also available, but the specific set depends on your system or printer configuration. Gnuplot simply refers to the font by name in the output file, and assumes that the printer or viewing program will know how to find or approximate a font by that name.Īll PostScript printers or viewers should know about the standard set of Adobe fonts Times-Roman, Helvetica, Courier, and Symbol. Gnuplot can create valid PostScript or encapsulated PostScript (*.eps) even if no fonts at all are installed on your computer. PostScript font handling is done by the printer or viewing program. Postscript (also encapsulated postscript *.eps) If no specific font is requested in the "set term" command, gnuplot checks the environmental variable GNUPLOT_DEFAULT_GDFONT to see if there is a preferred default font. To request a default font size at the same time: set term png font "arial,11"īoth TrueType and Adobe Type 1 fonts are fully scalable and rotatable. Set term png font "/usr/local/fonts/pfa/Helvetica.pfa" Set term png font "/usr/local/fonts/ttf/arial.ttf" For example, if GDFONTPATH contains /usr/local/fonts/ttf:/usr/local/fonts/pfa then the following pairs of commands are equivalent set term png font "arial" That is, 'set term png font "Face"' will look for a font file named either /Face.ttf or /Face.pfa. is either the full pathname to the font file, or the first part of a filename in one of the directories listed in the GDFONTPATH environmental variable. You must give the name of the font file, not the name of the font inside it, in the form " ". On most systems libgd also provides access to Adobe Type 1 fonts (*.pfa) and TrueType fonts (*.ttf). Use one of these keywords instead of the font keyword. These are tiny (5x8 pixels), small (6x12 pixels), medium, (7x13 Bold), large (8x16) or giant (9x15 pixels). Five basic fonts are provided directly by libgd. Set term pdfcairo font "Times-New-Roman,12"įont handling for the png, gif, jpeg, and sixelgd terminals is done by the library libgd. The following will probably all work: set term pdfcairo font "sans,12" It is usually sufficient in gnuplot to request a font by a generic name and size, letting fontconfig substitute a similar font if necessary. These terminals find and access fonts using the external fontconfig tool set. Cairo (pdfcairo, pngcairo, epscairo, wxt terminals) ![]() the Adobe Symbol font, the preferred method is now to specify the unicode entry point for the desired symbols using their UTF-8 encoding. For information on font use by other individual terminals, see the documentation for that terminal.Īlthough it is possible to include non-alphabetic symbols by temporarily switching to a special font, e.g. Brief documentation of font mechanisms that apply to more than one terminal type is given here. It relies on external font handling, the details of which unfortunately vary from one terminal type to another. Set xlabel " This is some figure text.Gnuplot does not provide any fonts of its own. Set term postscript eps enhanced color 'Helvetica' 15 ![]() I have 4 plots generated by the code: set size 1, 1 Dota 2 animajor1/31/2024 ![]() ![]() The latter was adored by fans, which serves to show that the audiences do overlap to an extent.ĭominik “Lacoste” Stipić, who participated as a caster, confirmed that. Moreover, even Dota 2, the main reason for the AniMajor in the first place, recently received its very own Netflix anime: DOTA Dragon's Blood. Some people were skeptical about the theme, but in the end, it was really well received – society as a whole has warmed towards youth entertainment such as esports and anime. The AniMajor was undoubtedly a successful event, and a part of its success was the anime vibe that was present throughout the whole tournament. The Chinese team took the prize of $200,000 and will head home with Tiny Airlines in wait for TI10. ![]() The WePlay Dota 2 AniMajor just had its winner – PSG.LGD defeated Evil Geniuses and claimed the champion's title. Combining Two Different Worlds Into a Spectacle The event was delightful as it masterfully managed to combine esports with anime. The AniMajor is over with PSG.LGD is the winner.
Ying yang git it1/31/2024 The average KD ratio in shGM2-CAR19 T cells and shGM4-CAR19 T cells reached 89% and 98.9%, respectively. The GM-CSF concentrations were 2,815.42 ng/ml in the shGM2-CAR19 T group and 284.22 ng/ml in the shGM4-CAR19 T group (Fig. The average GM-CSF concentration in the regular CAR19 T supernatant was 25,086.21 ng/ml. Cell supernatant was collected, and enzyme-linked immunosorbent assay (ELISA) experiments were conducted to detect the levels of GM-CSF. We used Nalm6 cells (a cell line of CD19 + B cell acute lymphoblastic leukemia) as target cells to coculture with CAR-T cells or mock T cells for 16 h. The transfected T cells were divided into five groups: mock T cells (GFP +), CAR19 T cells (CAR19 +, GFP +), shGM2-CAR19 T cells, shGM4-CAR19 T cells, and scramble-CAR19 T cells (Supplementary Fig. ![]() * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns: not significant)Ĭryopreserved human adult purified PBMCs were used to produce activated and amplified T cells. ( Each experiment was repeated for at least three times, and the results were expressed as mean (SD). The concentrations of IFN-α2, IL-12p70, IL-18, IL-23, and IL-33 were below the minimum value and not shown in this figure. (f) Cytokine profiles of co-cultured supernatants were measured by multi-analyte flow assay. (e) Concentration of GM-CSF (left) and IL-6 (right) in the supernatant collected after coculturing CAR-T/Nalm6/ CD14 + cells for 16 h assessed by ELISA. (d) Diagram of the space division of CAR-T, Nalm6 and CD14 + cells cocultured in transwell (pore size = 0.3 μm). (c) Cytotoxicity of conventional CAR19 T cells and GM-CSF KD CAR19 T cells were compared 12 h after cocultivation with Nalm6 Luc+ cells. Concentration of GM-CSF in the supernatant was analyzed by ELISA. (b) CAR-T cells (or mock T cells) were cocultured with CD19 + Nalm6 cells for 16 h. (a) Schematic presentation of the GM-CSF KD-shRNA-CAR19 construct used in this study. Regular manufacturing procedures would suffice to produce GM-CSF KD CAR-T cells and achieve comparable gene silencing efficiency to gene knockout, thereby promoting the clinical application of CAR-T cell therapy.Ĭharacterization and effects of GM-CSF KD CAR-T cells. In the present study, we inserted a short hairpin RNA (shRNA)-expression cassette in the CAR vector to reduce GM-CSF secreted by CAR-T cells. Meanwhile, the knockout efficiency of GM-CSF through double transduction could be unpredictable, and additional examinations would be needed. These additional manufacturing procedures might hamper the viability of CAR-T cells. However, these studies were conducted using CRISPR/Cas9 or TALENs, which require either a dual transduction of CAR-expressing vector and GM-CSF-gRNA-lentiCRISPRv2 lentiviruses or electroporation of mRNA encoding TRAC TALEN arms and subsequent AAV transfection to prepare GM-CSF KO CAR-T cells. Previous studies reported that gene editing of GM-CSF in CAR-T cells could prevent against adverse effects in vitro and in xenograft mouse models without damaging the cytotoxicity of CAR-T cells. Inflammatory cascade is thus initiated and leads to CRS and neurotoxicity. Stimulated monocytes–macrophages massively produce cytokines including IL-6 and IL-1. Activated CAR-T cells release various inflammatory cytokines including GM-CSF, which subsequently plays a major role in the stimulation and differentiation of innate monocytes–macrophages lineage. Various inflammatory factors were found elevated in serum samples after infusing CAR- T cells these factors include interleukin-6 (IL-6), interferon-γ (IFN-γ), granulocyte-macrophage colony-stimulating factor (GM-CSF), soluble interleukin-6 receptor (sIL-6R), macrophage inflammatory protein-1 (MCP-1), interleukin-1 (IL-1), etc. ![]() Cytokine release syndrome (CRS manifested by fever, hypotension, hypoxia, and target-organ damage) and neurotoxicity (characterized by headaches, confusion, seizure, and other neurologic manifestations) are the most representative. However, immunotherapy-associated side effects strongly hampered the development of CAR-T cell therapy, as severe complications are life-threatening for patients. Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated extraordinary potentials in the treatment of acute lymphocytic leukemia and B-cell lymphoma. AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |